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CAS Number :	108321-42-2
Product :	g-418 sulfate

G-418 sulfate (CAS No. 108321-42-2) is an aminoglycoside antibiotic similar in structure to gentamicin B1. It is commonly used in plant and mammalian cell culture as a selectable marker. It can be used to select for cells transformed with an iNOS promoter construct or neomycin resistance gene. G-418 functions by causing a chain of nonsense mutations during translation, ultimately resulting in inhibition of polypeptide synthesis and protein elongation. The product is imported as a white powder.